Brown University Center for Statistical Sciences Seminar
Abstract: Bodily growth rates often serve as primary outcomes in evaluations of anti-HIV therapies in children. We study a cohort of 1338 children assembled from participants in four pediatric AIDS clinical trials conducted in the Pediatric AIDS Clinical Trials Group. Data-analytic problems considered in this talk include a) algorithm and smoothing parameter selection for estimation of height and weight growth curves from irregular data; b) estimation and evaluation of quantile regression systems that model the age-dependence of location, dispersion, and skewness of cross-sectional distributions of growth velocities; c) evaluation of prognostic information present in growth velocity statistics and other markers of progression of HIV disease. This work is joint with Florence Yong, Ross McKinney, and Lisa Frenkel.
PDE Seminar
PDE Seminar
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