Division of Applied Mathematics

Seminars for Jan 10 - Jan 14, 2005

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• Thursday, January 13, 2005
  
  

  Brown University -
  Division of Biology and Medicine,
  Center for Statistical Sciences SEminar

  Speaker:	Hoa Nguyen, MS, Department of Statistics, Carnegie Mellon University
  Title:	The Faulty False Discovery Rate: How do Biased Nulls Influence FDR Calculations? Candidate for Assistant Professor (tenure track) in the Public Health Program/Department of Community Health
  Time/Place:	4:00 p.m., Hemisphere Building, 167 Angell Street, 1st floor Conference Room 106

  Abstract:   The false discovery rate (FDR) procedure introduced by Benjamini and Hochberg in 1995 has become a mainstream method for large scale simultaneous inference. The control of the procedure is contingent upon the assumption that null p-values are uniform. In this talk, we discuss power and control of the procedure when that assumption is violated. Our key example is drawn from a SNPs association analysis.

  This is joint work with Kathryn Roeder and Larry Wasserman.

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